CBDの副作用やリスクとは？過剰摂取は危険？

What are the side effects and risks of CBD? Is overdosing dangerous?

CBD has been a hot topic recently, but many people would like to understand the side effects before purchasing and using it. While the World Health Organization (WHO) has announced that CBD is a safe ingredient with no noticeable side effects, some studies have reported side effects, although they are not serious.

This article summarizes the side effects that have been reported so far.

table of contents

  1. What is CBD?
  2. What are the side effects of CBD?
  3. lastly

What is CBD?

Cannabidiol (CBD) is a type of cannabinoid, a type of natural compound found in cannabis and hemp. Since 2018, the production of CBD products has increased and they have recently attracted a lot of attention.


What are the side effects of CBD?

Here is a list of side effects of CBD that have been reported in previous studies.

  • Changes in appetite
  • Weight change
  • Drowsiness or fatigue
  • diarrhea
  • Dizziness/lightheadedness
  • Dry mouth
  • Effects on the liver

In addition to the above, there are side effects and potential risks for those who are breastfeeding, small children, those with mobility impairments, those with chronic illnesses, etc. At this time, the reported side effects have been kept to a minimum compared to prescription drugs, and there have been no reports of serious symptoms.


Changes in appetite

Changes in appetite are a commonly reported side effect, although research has been mixed on whether CBD increases or decreases appetite. The endocannabinoid system (ECS) is natural to the human body, but CBD oil is known to react with other substances that affect the gut.

 

Weight change

Changes in appetite lead to changes in weight. When CBD causes changes in metabolism, it also affects weight. Although this is called a side effect, it has been reported that CBD oil may also be effective in weight loss.

 

Drowsiness

CBD is known to affect sleep. Therefore, I think that many people with insomnia use it. However, fatigue and drowsiness can appear as side effects. The effects of CBD vary from person to person. Some reports say that using CBD makes you feel more awake, energized, and alert. Examples of drowsiness reported as a side effect tend to occur especially after taking large amounts of CBD.

 

diarrhea

Diarrhea is a commonly reported side effect of taking too much CBD, but it is unclear whether this is caused by CBD or other additives or ingredients. Studies have shown that diarrhea is one of the most common side effects of CBD.

 

Dizziness/lightheadedness

Dizziness and lightheadedness are rare side effects of CBD, and if they do occur, they are usually temporary. These symptoms are usually accompanied by drowsiness, but can be improved by minimizing caffeine intake (coffee or tea) and exercise. These symptoms can also occur if you experience a drop in blood pressure, a known side effect of CBD.

 

Dry mouth

CBD is one of over 100 cannabinoids found in the cannabis plant, but a common side effect of all cannabinoids is the dry mouth.

 

Effects on the liver

CBD has been reported to potentially inhibit enzymes in the liver, and there are concerns about its interactions with other medications.

What happens if you take too much CBD?

You may be wondering what happens if you take large amounts of CBD, but past studies have shown that taking up to 1,500 mg of CBD per day is not harmful to the body.

A study conducted in 2007 reported the following:

The recommended dosage is usually between 10mg and 30mg per day. Therefore, it is unlikely that you would realistically consume a higher dose than this in your everyday life, so there is no need to worry about taking too much CBD unless there is a very good reason.

Additionally, CBD is not addictive like THC, so even if you take large amounts of CBD, you will not experience any symptoms of intoxication.

However, it is not that there is absolutely nothing wrong with it, and as mentioned above, a major characteristic of CBD products is that the effects and side effects manifest differently from person to person.

Although it is believed that there is generally no harm in taking large amounts, if you take too much CBD without considering the amount you need, you may experience unnecessary side effects or interactions.

When taking CBD or CBD oil, be sure to find the dosage that is right for you and be careful not to take too much CBD.

Does CBD cause allergies?

We've already covered the side effects of CBD, but it can also cause allergic reactions.

An allergic reaction is an exaggerated immune response to a specific antigen, where the body attacks what it considers to be an allergen. Common allergens include house dust, pet hair, pollen, food, and drugs.

Because CBD is extracted from plants, it cannot be said that it will not cause an allergic reaction, as it contains pollen that the body may consider an allergen, as well as histamine, which can cause the allergic reaction itself.

It is said that the symptoms of CBD-induced allergies are similar to those of seasonal plant allergies and hay fever.

Symptoms of allergies include a dry cough, sneezing, runny nose, nausea, red or itchy eyes, sore throat, and hives.

These symptoms are said to go away if you stop using CBD oil, but if you experience symptoms that seem like an allergy, stop using CBD and observe the condition.

If you experience any symptoms that are obviously different from usual, such as difficulty breathing, fainting, or confusion, or if your allergic symptoms are severe, be sure to see your doctor immediately.

It can be said that CBD is not good for everyone.

Beware of interactions when using CBD with medicines

Some people who take CBD may take it in combination with medicines, but in that case, care should be taken as there may be negative effects depending on the drug combination.

For example, CBD has the effect of inhibiting detoxification in the liver. High doses of CBD, in particular, are said to inhibit liver enzymes (CYP450).

Caution is advised when taking high doses of CBD in combination with the following medications:

Steroids, immunosuppressants, statins, antibiotics, NSAIDs, ARBs, calcium antagonists, beta blockers, antihistamines, benzodiazepines, antidepressants, antipsychotics, anesthetics, proton pump inhibitors, gastrointestinal motility improving drugs, oral hypoglycemic agents, sulfonylurea drugs, antiarrhythmic drugs, anti-HIV drugs

It is said that taking CBD with medication can result in the medication remaining in the body without being detoxified, which can have adverse effects on the body.

Grapefruit is one of the substances that has a similar effect to CBD and can affect concomitant medications.

Grapefruit also has an inhibitory effect on hepatic detoxification and may slow down the detoxification of concomitant medications.

This is an area where it can be quite difficult to judge on your own, so we recommend that you do not make your own judgment.If you are already taking other medications and want to use CBD, we recommend that you consult with your doctor.

lastly

This article introduces the side effects of CBD that have been reported so far. Although no serious damage has occurred as long as the dosage is adhered to, it is better to be aware of these side effects. We recommend that you consult your doctor about interactions with medications you are taking.

References

Notes

  • The information on the effects, efficacy, and side effects of CBD provided by our company is provided for informational purposes. The scientific research described is on the ingredients of CBD, not on the products we handle, and has no direct relationship to the effects of the CBD products we handle.
  • CBD products are not medicines and are not intended to diagnose, treat or cure any disease or symptoms.
  • The articles and information we provide are created and provided based on sources that we deem reliable, but we do not guarantee their completeness, accuracy, etc.